As announced today, the PROXIDRUGS consortium has been selected for funding within the Clusters4Future initiative of the Federal Ministry of Education and Research (BMBF), which aims at promoting regional innovation networks for the benefit of economy and society. PROXIDRUGS will be funded with up to 15 M € for the next three years, as only one of 7 clusters selected for funding from a total of 137 applications.
The consortium concentrates on developing new treatments for diseases with high unmet medical need by utilizing the new concept of proximity induction in drug design. It is assumed that 80% of the proteins that are so far deemed as undruggable may be targeted by this strategy. “Proxidrugs open up exciting new therapeutic options in numerous diseases including cancer, neurodegeneration and infection. Proxidrugs can trigger degradation of disease-relevant proteins in a highly specific fashion by directing them towards the cellular recycling system”, explains cluster speaker Ivan Đikić from Goethe University.
PROXIDRUGS has been set up as a regional network of partners from academia and industry, covering the entire value chain from basic to translational research. Academic participants are based at Goethe University Frankfurt, TU Darmstadt, University of Heidelberg, the MPI of Biophysics and the Fraunhofer Institute for Translational Medicine and Pharmacology, and they are closely working together with major pharma partners.
At Goethe University, the Frankfurt Center for Innovation & Technologies will be established as academic innovation hub that provides the needed technologies to the consortium. Ivan Đikić adds: “The early and close collaboration between all partners marks the start of a new era in drug development within the Rhine Main region. This culture of teamwork and sharing knowledge paves the way for an efficient transfer towards therapeutic applications.”
06. Mar 2023 18:00h
Location: GU Frankfurt - Uniklinik Haus 22, Hörsaal 2
Hybrid Lecture
26. Sep 2022 16:15h
Location: Lecture Hall H20-5, Bldg. 20, Campus Niederrad
Hybrid Lecture
18. Jan 2022 16:00h
Location: Virtual Meeting
Virtual Lecture
22. Nov 2021 17:00h
Location: Auditorium H2, Otto-Stern-Zentrum, Riedberg Campus
Hybrid Lecture
27. Oct 2021 16:00h
Location: UKF, Building 23, auditorium 23-3
Hybrid Lecture
14. Sep 2021 17:00h
Location: Virtual Meeting
Virtual Lecture
25. May 2021 15:00h
Location: to be announced
Virtual Lecture
29. Sep 2020 16:00h
Location: Virtual Lecture via Zoom; Meeting-ID: 962 0881 2086 Kenncode: 612251
Virtual Lecture
PROXIDRUGS-Clusterbüro
Institut für Biochemie II
Goethe-Universität Frankfurt - Fachbereich Medizin
Universitätsklinikum - Gebäude 75
Theodor-Stern-Kai 7
60590 Frankfurt am Main/Germany
Email proxidrugs@uni-frankfurt.de
Telefon +49 (0) 69 6301-84972
